This test is unlike standard liver function tests which only provide a measure of hepatic damage (released hepatic enzyme levels). In contrast, the liver detoxification test is a true functional test as it evaluates the ability of an individual to process caffeine, aspirin (salicylate) and paracetamol (acetaminophen) by assessing certain metabolites in salivary and urinary specimens. Specific measurements of the different phases of liver detoxification including phase I and phase II (glycination, glucuronidation, sulphation and glutathionation) are obtained, guiding the design of effective and specific therapeutic strategies which can optimise liver function.